Senior Scientist I Analytical Development - Oxford

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Senior Scientist I Analytical Development - Oxford

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.

At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits.

Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.

As Senior Scientist I, Analytical Development, you will help execute analytical strategies across Immunocore's therapeutic project portfolio, driving the development and oversight of robust impurity analytical methods and control strategies. Acting within cross-functional teams, you'll provide technical consultancy and guide the technical transfer and validation of assays at contract manufacturers. Your role will be instrumental in delivering high-quality data and impactful contributions to the advancement of Immunocore's therapeutic pipeline.

Key Responsibilities

* Contribute to analytical program strategies across our therapeutic project portfolio
* Represent analytical development within cross-functional project teams, providing strategic support and technical consultancy
* Develop and qualify analytical methods for biopharmaceutical process analysis, and process related impurity testing, including methods such as host cell protein ELISA, 2D Western blotting, host cell DNA and/or endotoxin assays as well as HPLC of residual impurities
* Contribute to development and control of critical reagents for biopharmaceutical assays
* Oversee technical transfer and validation of assays at contract manufacturers in line with ICH regulatory guidelines, and develop phase appropriate specifications
* Contribute towards relevant sections of CMC regulatory documentation, e.g., IND, IMPD, BLA, MAA and help responses to any agency questions
* Develop scientists of lower grades within the analytical development team
* Prepare reports and presentations of high quality suitable for internal and external audiences.
* Independently test and, increasingly, lead lines of investigation. Propose new experiments based on emerging data and other related information. Provide support on technical aspects to others.
* Priorities: establish priorities for own work and team-based projects; make decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance.
* Technical Knowledge: share knowledge with the wider team and, across departments representing the department both internally and externally. Increasingly provide analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the Company.
* Laboratory records: ensure that all records and information are up to date, on time and recorded to the correct standard.
* Laboratory equipment: provide technical guidance to others within the team on how to use equipment most effectively; making recommendations regarding acquisition of new pieces of equipment.
* Adhere to safe working practices in laboratories according to Immunocore EHS policies.

Experience & knowledge

Essential

* Experience in development of methods for analysis of recombinant proteins or antibodies.
* Worked in a biopharmaceutical laboratory environment.
* Hands on expertise of SDS PAGE, Western blotting of proteins and impurity testing experience (one or more of host cell protein ELISA, host cell DNA (qPCR), endotoxin, process residuals).
* Experience with early and late stage/commercial biopharmaceutical drug programs
* Presented detailed scientific findings to internal and external audiences.
* Mentored and coached less experienced colleagues in scientific practices and theory.

Desirable

* Experience with HCP coverage assessments and strategy
* Knowledge of GMP
* Experience with managing analytical activities at Contract Manufacturers.
* Led a small project team, formally or informally, through a change in practice including project management.

Education & qualifications

* Essential: BSc. Or MSc. in biochemistry, biotechnology or related discipline
* Desirable: PhD in related discipline

How to Submit an Application:

After reading and knowing the criteria and minimum requirements for qualifications that have been explained from the Senior Scientist I Analytical Development - Oxford job info - Immunocore Oxford above, thus jobseekers who feel they have not met the requirements including education, age, etc. and really feel interested in the latest job vacancies Senior Scientist I Analytical Development - Oxford job info - Immunocore Oxford in 2025-10-24 above, should as soon as possible complete and compile a job application file such as a job application letter, CV or curriculum vitae, FC diploma and transcripts and other supplements as described above, in order to register and take part in the admission selection for new employees in the company referred to, sent via form this bottom.